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http://hdl.handle.net/11434/285
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DC Field | Value | Language |
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dc.contributor.author | O'Sullivan, Richard | en |
dc.contributor.other | Teichtahl, Andrew | en |
dc.contributor.other | Urquhart, Donna | en |
dc.contributor.other | Wang, Yuanyuan | en |
dc.contributor.other | Wluka, Anita | en |
dc.contributor.other | Jones, Graeme | en |
dc.contributor.other | Cicuttini, Flavia | en |
dc.date | 2015 | en |
dc.date.accessioned | 2015-07-27T22:37:10Z | en |
dc.date.available | 2015-07-27T22:37:10Z | en |
dc.date.issued | 2015-05 | en |
dc.identifier.citation | Arthritis and Research Therapy 2015 May 7;17(1):114 | en |
dc.identifier.issn | 1478-6354 | en |
dc.identifier.uri | http://hdl.handle.net/11434/285 | en |
dc.description.abstract | INTRODUCTION: Although physical inactivity has been associated with numerous chronic musculoskeletal complaints, few studies have examined its associations with spinal structures. Moreover, previously reported associations between physical activity and low back pain are conflicting. This study examined the associations between physical inactivity and intervertebral disc height, paraspinal fat content and low back pain and disability. METHODS: Seventy-two community-based volunteers not selected for low back pain underwent magnetic resonance imaging (MRI) of their lumbosacral spine (L1 to S1) between 2011 and 2012. Physical activity was assessed between 2005 and 2008 by questionnaire, while low back pain and disability were assessed by the Chronic Pain Grade Scale at the time of MRI. Intervertebral disc height and cross-sectional area and fat content of multifidus and erector spinae were assessed from MRI. RESULTS: Lower physical activity levels were associated with a more narrow average intervertebral disc height (β -0.63 mm, 95% confidence interval (CI) -1.17 mm to -0.08 mm, P = 0.026) after adjusting for age, gender and body mass index (BMI). There were no significant associations between physical activity levels and the cross-sectional area of multifidus or erector spinae. Lower levels of physical activity were associated with an increased risk of high fat content in multifidus (odds ratio (OR) 2.7, 95% CI 1.1 to 6.7, P = 0.04) and high-intensity pain/disability (OR = 5.0, 95% CI 1.5 to 16.4, P = 0.008) after adjustment for age, gender and BMI. CONCLUSIONS: Physical inactivity is associated with narrower intervertebral discs, high fat content of the multifidus and high-intensity low back pain and disability in a dose-dependent manner among community-based adults. Longitudinal studies will help to determine the cause and effect nature of these associations. | en |
dc.publisher | BioMed Central | en |
dc.subject | MRI Department, Healthcare Imaging Services, Epworth HealthCare, Victoria, Australia | en |
dc.subject | Body Mass Index | en |
dc.subject | Confidence Intervals | en |
dc.subject | Cross-Sectional Area | en |
dc.subject | Statistics, Nonparametric | en |
dc.subject | Magnetic Resonance Imaging | en |
dc.subject | MRI Scans | en |
dc.subject | Odds Ratio | en |
dc.subject | Risk Ratio | en |
dc.subject | Relative Odds | en |
dc.subject | Physical Activity | en |
dc.subject | Motor Activity | en |
dc.subject | Locomotor Activity | en |
dc.subject | Paraspinal Muscles | en |
dc.subject | Multifidus | en |
dc.subject | Deep Muscles of the Back | en |
dc.subject | Intervertebral Disc Disease | en |
dc.subject | Lumbar Disc Disease | en |
dc.subject | Low Back Pain | en |
dc.subject | Lower Back Pain | en |
dc.subject | Intervertebral Disc | en |
dc.subject | Disc, Intervertebral | en |
dc.subject | Obesity | en |
dc.subject | Body Weight | en |
dc.subject | Zygapophyseal Joint | en |
dc.subject | Facet Joint | en |
dc.subject | Chronic Pain | en |
dc.subject | Pain, Chronic | en |
dc.title | Physical inactivity is associated with narrower lumbar intervertebral discs, high fat content of paraspinal muscles and low back pain and disability. | en |
dc.type | Journal Article | en |
dc.identifier.doi | 10.1186/s13075-015-0629-y | en |
dc.identifier.journaltitle | Arthritis and Research Therapy | en |
dc.description.pubmeduri | http://www.ncbi.nlm.nih.gov/pubmed/25947906 | en |
dc.description.affiliates | Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Alfred Hospital, Melbourne, Victoria, Australia | en |
dc.description.affiliates | Baker IDI Heart and Diabetes Institute, Melbourne, Victoria, Australia | en |
dc.description.affiliates | Department of Medicine, Central Clinical School, Monash University, Melbourne, Victoria, 3004, Australia | en |
dc.description.affiliates | Menzies Research Institute, Hobart, Tasmania, Australia | en |
dc.type.studyortrial | Prospective Cohort Study | en |
dc.type.contenttype | Text | en |
Appears in Collections: | Musculoskeletal Pain Management |
Files in This Item:
File | Description | Size | Format | |
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Physical inactivity is associated with narrower.pdf | Main article | 549.63 kB | Adobe PDF | View/Open |
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