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Title: The phytological future of prostate cancer staging: prostate-specific membrane antigen positron emission tomography and the dandelion theory.
Epworth Authors: Murphy, Declan
Lawrentschuk, Nathan
Other Authors: Sathianathen, Niranjan
Geurts, Nicolas
Nair, Rajesh
Lamb, Alastair
Keywords: Positron Emission Tomography
Prostate Cancer
Dandelion Theory
Prostate-Specific Membrane Antigen
Lymph Nodes
Metastatic Prostate
Australian Prostate Cancer Research Centre Epworth HealthCare, Victoria, Australia
UroRenal, Vascular Clinical Institute, Epworth HealthCare, Victoria, Australia
Issue Date: Aug-2017
Publisher: Future Science Group
Citation: Future Oncol. 2017 Aug;13(20):1801-1807
Abstract: PSMA-PET is changing how we stage prostate cancer, both in the primary setting and with relapse after treatment. It allows us to identify lesions in the bones and lymph nodes that were not previously visible on conventional imaging with bone scan and CT/MRI. In this Special Report we review the 'state of the art' for PSMA imaging and discuss the implications for treatment decisions in prostate cancer. We liken early high risk or metastatic prostate to a common phytological problem: the dandelion. In this analogous situation, we consider the additional evidence needed for us to start plucking out the original dandelion and for us to focus attention on killing the seeded weeds that are identifiable elsewhere in the lawn.
DOI: 10.2217/fon-2017-0074
PubMed URL:
ISSN: 1479-6694
Journal Title: Future Oncology
Type: Journal Article
Affiliated Organisations: Department of Genitourinary Oncology & Division of Cancer Surgery, Peter MacCallum Cancer Centre, The University of Melbourne, Victoria, Australia.
Department of Surgery, Austin Health, The University of Melbourne, Victoria, Australia.
Academic Urology Group, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK.
Nuffield Department of Surgical Sciences, University of Oxford, UK.
Type of Clinical Study or Trial: Review
Appears in Collections:Cancer Services
Epworth Prostate Centre

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