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Title: Warmed, humidified CO2 insufflation benefits intraoperative core temperature during laparoscopic surgery: A meta-analysis.
Epworth Authors: Dean, Meara
Mackay, John
Hiscock, Richard
Lynch, A. Craig
Heriot, Alexander
Other Authors: Ramsay, Robert
Keywords: Laparoscopy
Intraoperative Hypothermia
Abdominal Surgery
Warmed Humidified CO2
Cold Dry CO2
Intraoperative Core Temperature
Postoperative Adverse Events
Cancer Services Clinical Institute, Epworth HealthCare, Victoria, Australia
General Surgery and Gastroenterology Clinical Institute, Epworth HealthCare, Victoria, Australia
Issue Date: Dec-2016
Publisher: Wiley Online Library
Citation: Asian J Endosc Surg. 2016 Dec 14.
Abstract: BACKGROUND: Intraoperative hypothermia is linked to postoperative adverse events. The use of warmed, humidified CO2 to establish pneumoperitoneum during laparoscopy has been associated with reduced incidence of intraoperative hypothermia. However, the small number and variable quality of published studies have caused uncertainty about the potential benefit of this therapy. This meta-analysis was conducted to specifically evaluate the effects of warmed, humidified CO2 during laparoscopy. METHODS: An electronic database search identified randomized controlled trials performed on adults who underwent laparoscopic abdominal surgery under general anesthesia with either warmed, humidified CO2 or cold, dry CO2 . The main outcome measure of interest was change in intraoperative core body temperature. RESULTS: The database search identified 320 studies as potentially relevant, and of these, 13 met the inclusion criteria and were included in the analysis. During laparoscopic surgery, use of warmed, humidified CO2 is associated with a significant increase in intraoperative core temperature (mean temperature change, 0.3°C), when compared with cold, dry CO2 insufflation. CONCLUSION: Warmed, humidified CO2 insufflation during laparoscopic abdominal surgery has been demonstrated to improve intraoperative maintenance of normothermia when compared with cold, dry CO2.
DOI: 10.1111/ases.12350
PubMed URL:
ISSN: 1758-5902
Journal Title: Asian Journal of Endoscopic Surgery
Type: Journal Article
Affiliated Organisations: Division of Cancer Surgery, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.
Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Victoria, Australia.
Department of Surgery, St Vincent's Hospital, University of Melbourne, Melbourne, Victoria, Australia.
Type of Clinical Study or Trial: Meta-Analysis
Appears in Collections:Cancer Services
General Surgery and Gastroenterology

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