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http://hdl.handle.net/11434/96| Title: | Curated microRNAs in urine and blood fail to validate as predictive biomarkers for high-risk prostate cancer. |
| Epworth Authors: | Sapre, Nikhil Hong, Matthew Lewis, Heather Costello, Anthony Corcoran, Niall Hovens, Christopher |
| Other Authors: | Macintyre, Geoff Kowalczyk, Adam |
| Keywords: | Prostate Cancer Prostatic Neoplasms MicroRNAs Biological Markers Prostate Genetic Testing Prostatectomy Australian Prostate Cancer Research Epworth, Richmond, Victoria, Australia. |
| Issue Date: | Apr-2014 |
| Citation: | PLoS One. 2014 Apr 4;9(4):e91729. eCollection 2014. |
| Abstract: | The purpose of this study was to determine if microRNA profiling of urine and plasma at radical prostatectomy can distinguish potentially lethal from indolent prostate cancer. A panel of microRNAs was profiled in the plasma of 70 patients and the urine of 33 patients collected prior to radical prostatectomy. Expression of microRNAs was correlated to the clinical endpoints at a follow-up time of 3.9 years to identify microRNAs that may predict clinical response after radical prostatectomy. |
| URI: | http://hdl.handle.net/11434/96 |
| DOI: | 10.1371/journal.pone.0091729 |
| PubMed URL: | http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3976264/ |
| ISSN: | 1932-6203 |
| Journal Title: | PLoS One (Public Library of Science). |
| Type: | Journal Article Text |
| Affiliated Organisations: | Division of Urology, Department of Surgery, Royal Melbourne Hospital and the University of Melbourne, Parkville, Victoria, Australia NICTA Victoria Research Laboratory, Department of Electronic and Electrical Engineering, The University of Melbourne, Parkville, Victoria, Australia Department of Computing and Information Systems, The University of Melbourne, Parkville, Victoria, Australia |
| Type of Clinical Study or Trial: | Validation Study |
| Appears in Collections: | Cancer Services Epworth Prostate Centre UroRenal, Vascular |
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