Please use this identifier to cite or link to this item: http://hdl.handle.net/11434/864
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dc.contributor.authorGilligan, Amanda-
dc.contributor.otherNg, F. C.-
dc.contributor.otherChoi, P. M.-
dc.contributor.otherDatta, M.-
dc.date2016-07-
dc.date.accessioned2016-11-08T01:10:58Z-
dc.date.available2016-11-08T01:10:58Z-
dc.date.issued2016-11-
dc.identifier.citationJ Neuroimaging. 2016 Nov;26(6):588-591. doi: 10.1111/jon.12375en_US
dc.identifier.issn1552-6569en_US
dc.identifier.urihttp://hdl.handle.net/11434/864-
dc.description.abstractBACKGROUND: Differentiation between true acute tandem occlusion involving the extracranial internal carotid artery (ICA) from pseudotandem occlusion with a patent extracranial ICA has important prognostic and therapeutic implications. We explored the utility of perfusion-derived 4-dimensional CT angiogram (4D-CTA) in identifying carotid pseudo-occlusion in a single-center pilot study. METHODS: Acute stroke patients with delayed antegrade ICA flow on 4D-CTA despite an apparent tandem occlusion on conventional single-phase CTA were prospectively identified over a 2.5-year period (2013-2015). RESULTS: Eight patients were identified. Delayed antegrade intracranial flow from the apparently occluded ICA was detected up to 50 seconds after contrast administration on 4D-CTA. The distal intracranial ICA was the most common site of true occlusion. Reconstruction of the 4D-CTA images required an additional processing time of 2-3 minutes. CONCLUSIONS: 4D-CTA is a novel noninvasive technique that can identify carotid pseudo-occlusion in the acute stroke setting. Our preliminary findings suggest that 4D-CTA can be easily incorporated into an existing acute stroke neuroimaging protocol.en_US
dc.publisherWiley Online Libraryen_US
dc.subjectEndovascular Interventionen_US
dc.subjectAcute Strokeen_US
dc.subjectCarotid Pseudo-Occlusionen_US
dc.subjectCT Perfusionen_US
dc.subject4-Dimensional CT Angiogramen_US
dc.subject4D-CTAen_US
dc.subjectExtracranial Internal Carotid Arteryen_US
dc.subjectICAen_US
dc.subjectAcute Tandem Occlusionen_US
dc.subjectNeurosciences Clinical Institute, Epworth HealthCare, Victoria, Australiaen_US
dc.titlePerfusion-derived dynamic 4D CT angiography identifies carotid pseudo-occlusion in hyperacute stroke.en_US
dc.typeJournal Articleen_US
dc.identifier.doi10.1111/jon.12375en_US
dc.identifier.journaltitleJournal of Neuroimagingen_US
dc.description.pubmedurihttps://www.ncbi.nlm.nih.gov/pubmed/27383381en_US
dc.description.affiliatesDepartment of Neurosciences, Box Hill Hospital, Melbourne, Victoria, Australia.en_US
dc.description.affiliatesEastern Health Clinical School, Faculty of Medicine, Nursing and Health Sciences, Monash University, Melbourne, Victoria, Australia.en_US
dc.description.affiliatesDepartment of Medical Imaging, Box Hill Hospital, Melbourne, Victoria, Australia.en_US
dc.type.studyortrialObservational Studyen_US
dc.type.contenttypeTexten_US
Appears in Collections:Diagnostic Services
Neurosciences

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