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Title: Proceedings from an international consensus meeting on posttransplantation diabetes mellitus: recommendations and future directions.
Epworth Authors: Cohney, Solomon (Shlomo)
Other Authors: Sharif, Adnan
Hecking, Manfred
de Vries, Aiko
Porrini, E.
Hornum, M.
Rasoul-Rockenschaub, Susanne
Berlakovich, Gabriela
Krebs, Michael
Kautzky-Willer, Alexandra
Schernthaner, G.
Marchetti, Piero
Pacini, Giovanni
Ojo, Akinlolu
Takahara, S.
Larsen, J. L.
Budde, K.
Eller, Kathrin
Pascual, J.
Jardine, Alan
Bakker, S. J. L.
Valderhaug, T. G.
Jenssen, T. G.
Saemann, Marcus
Keywords: Consensus
Diabetes Mellitus
Adverse Effects
Diagnostic Challenges
Therapeutic Challenges
Posttransplantation Diabetes Mellitus
UroRenal, Vascular Clinical Institute, Epworth HealthCare, Victoria, Australia
Department of Nephrology, Epworth HealthCare, Richmond, Victoria, Australia.
Department of Gastroenterology, Epworth HealthCare, Richmond, Victoria, Australia.
Issue Date: Sep-2014
Publisher: Wiley
Citation: Am J Transplant. 2014 Sep;14(9):1992-2000.
Abstract: A consensus meeting was held in Vienna on September 8-9, 2013, to discuss diagnostic and therapeutic challenges surrounding development of diabetes mellitus after transplantation. The International Expert Panel comprised 24 transplant nephrologists, surgeons, diabetologists and clinical scientists, which met with the aim to review previous guidelines in light of emerging clinical data and research. Recommendations from the consensus discussions are provided in this article. Although the meeting was kidney-centric, reflecting the expertise present, these recommendations are likely to be relevant to other solid organ transplant recipients. Our recommendations include: terminology revision from new-onset diabetes after transplantation to posttransplantation diabetes mellitus (PTDM), exclusion of transient posttransplant hyperglycemia from PTDM diagnosis, expansion of screening strategies (incorporating postprandial glucose and HbA1c) and opinion-based guidance regarding pharmacological therapy in light of recent clinical evidence. Future research in the field was discussed with the aim of establishing collaborative working groups to address unresolved questions. These recommendations are opinion-based and intended to serve as a template for planned guidelines update, based on systematic and graded literature review, on the diagnosis and management of PTDM.
DOI: 10.1111/ajt.12850
PubMed URL:
ISSN: 1600-6135
Journal Title: American Journal of Transplantation
Type: Journal Article
Affiliated Organisations: Department of Nephrology and Transplantation, Queen Elizabeth Hospital, Birmingham, UK.
Department of Internal Medicine, Medical University of Vienna, Vienna, Austria.
Division of Nephrology and Transplant Medicine, Department of Medicine, Leiden University Medical Center, Leiden, the Netherlands.
Center for Biomedical Research of the Canary Islands, CIBICAN, University of La Laguna, Tenerife, Spain.
Department of Nephrology, Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.
Department of Endocrinology and Metabolism, University of Pisa, Pisa, Italy.
Metabolic Unit, Institute of Biomedical Engineering, National Research Council, Padova, Italy.
Division of Nephrology, University of Michigan Health System, Ann Arbor, MI.
Department of Advanced Technology for Transplantation, Osaka University Graduate School of Medicine, Osaka, Japan.
Department of Internal Medicine, Nebraska Medical Center, Omaha, NE.
Department of Nephrology, Charité University, Berlin, Germany.
Clinical Division of Nephrology, Medical University of Graz, Graz, Austria.
Servicio de Nefrología, Hospital del Mar, Parc de Salut Mar, Barcelona, Spain.
Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK.
Department of Internal Medicine, University Medical Center Groningen and University of Groningen, Groningen, the Netherlands.
Department of Endocrinology, Akershus University Hospital, Lorenskog, Norway.
Department of Organ Transplantation, Oslo University Hospital, Rikshospitalet, Oslo, Norway.
Department of Nephrology, Royal Melbourne and Western Hospitals, Melbourne, Australia.
Appears in Collections:Internal Medicine
UroRenal, Vascular

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