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Title: Role of cytoreductive prostatectomy in non-organ confined prostate cancer.
Epworth Authors: Murphy, Declan
Moon, Daniel
Other Authors: Sathianathen, Niranjan
Keywords: Prostatectomy
Radical Prostatectomy
Prostate Cancer
Cytoreductive Surgery
Metastatic Disease
Androgen Deprivation Therapy
Prostate Specific Antigen Screening
Australian Prostate Cancer Research Centre, Epworth Healthcare, Victoria, Australia
UroRenal, Vascular Clinical Institute, Epworth HealthCare, Victoria, Australia
Issue Date: Nov-2015
Publisher: Cancer Council Australia
Citation: Cancer Forum. 2015 November; 39 (3): pp 178-182
Abstract: Prostate cancer is the most common cancer among Australian men. Despite the surrounding controversies, prostate specific antigen screening has resulted in diagnosis being made at a stage in which the cancer is still confined to the prostate in the majority of cases. However, there is still a small subset of men who are not diagnosed until after the cancer has metastasised. Historically, these cases have been managed with androgen deprivation therapy with no role for surgery. However, with data supporting cytoreductive surgery in other cancers such as kidney, breast and ovarian, there is increasing interest in the role of surgery as part of a multimodal approach to men with metastatic prostate cancer. Early data suggest that surgery in this situation is feasible and safe, with encouraging data suggesting an oncological benefit. Randomised trials are underway to establish who might benefit and which strategy should be incorporated. In the meantime, radical prostatectomy in the context of metastatic disease should be considered experimental.
ISSN: 0311-306X
Journal Title: Cancer Forum
Type: Journal Article
Affiliated Organisations: Division of Cancer Surgery, University of Melbourne, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia
Faculty of Medicine, Monash University, Melbourne, Victoria, Australia
Type of Clinical Study or Trial: Case Series and Case Reports
Appears in Collections:Cancer Services
Epworth Prostate Centre
UroRenal, Vascular

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