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Title: Focal therapy for localised prostate cancer: are we asking the correct research questions?
Epworth Authors: Murphy, Declan
Costello, Anthony
Other Authors: Walton, Thomas
Connolly, Stephen
Keywords: Focal therapy for localised prostate cancer
Prostate Cancer
Focal Therapy
Catheter Ablation
Neoplasm Staging
Australian Prostate Cancer Research Centre, Epworth Richmond
Prostatic Neoplasms
Index Lesion
Issue Date: Jan-2012
Publisher: Wiley-Blackwell
Citation: BJU Int. 2012 Jan;109(1):1-3
Abstract: The goals of focal therapy are laudable, namely reducing morbidity of treatment while ensuring at least equivalent oncological outcomes when compared with established interventions for localised prostate cancer, e.g. RP and external beam radiotherapy. While progress has been made towards better identifying the index lesion in these patients, there is much yet to be done to establish the validity of the index lesion theory as the metastatic focus and to establish that current targeting and ablative platforms are adequate to deliver the goals outlined above. The correct research questions have not yet been asked to establish either of these key principles underpinning focal therapy for localised prostate cancer.
DOI: 10.1111/j.1464-410X.2011.10804.x
PubMed URL:
ISSN: 1464-4096
Journal Title: BJU international
Type: Journal Article
Affiliated Organisations: The Peter MacCallum Cancer Centre, Melbourne
Royal Melbourne Hospital, Melbourne, Vict., Australia
Type of Clinical Study or Trial: Review
Appears in Collections:Cancer Services
Epworth Prostate Centre
UroRenal, Vascular

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