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http://hdl.handle.net/11434/374| Title: | Assessing pathological complete response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer: a systematic review. |
| Epworth Authors: | Ryan, Jennifer Warrier, Satish Lynch, A. Craig Heriot, Alexander |
| Keywords: | Epworth Healthcare, Melbourne, Victoria, Australia Neoadjuvant Chemoradiotherapy Locally Advanced Rectal Cancer Rectal Cancer Chemoradiotherapy Rectal Neoplasm Neoadjuvant Therapy Response Epworth Cancer Services Clinical Institute, Epworth HealthCare, Victoria, Australia Cancer Services Clinical Institute, Epworth HealthCare, Victoria, Australia |
| Issue Date: | Oct-2015 |
| Publisher: | Wiley |
| Citation: | Colorectal Dis. 2015 Oct;17(10):849-61 |
| Abstract: | AIM: Pathological complete response to neoadjuvant chemoradiotherapy is found in 20% of patients with rectal cancer undergoing long-course chemoradiotherapy. Some authors have suggested that these patients do not need to undergo surgery and can be managed with careful follow-up, with surgery only used in the event of clinical failure. Widespread adoption of this regimen is limited by the accuracy of methods to confirm a pathological complete response (pCR). |
| URI: | http://hdl.handle.net/11434/374 |
| DOI: | 10.1111/codi.13081 |
| PubMed URL: | http://www.ncbi.nlm.nih.gov/pubmed/26260213 |
| ISSN: | 1463-1318 |
| Journal Title: | Colorectal Disease |
| Type: | Journal Article |
| Affiliated Organisations: | Department of Cancer Surgery, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia Austin Academic Centre, University of Melbourne, Melbourne, Victoria, Australia |
| Type of Clinical Study or Trial: | Systematic Reviews |
| Appears in Collections: | Cancer Services General Surgery and Gastroenterology |
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