Does heparin and aspirin improve IVF success rate?

Abstract

Poster presentation. Aim: To systematically review studies that involve the usage of heparin and aspirin to improve IVF success rate. Methods: Literature articles search was performed at October 2014. PUBMED is used to search the studies for this systematic review with keywords “IVF & Heparin” and “IVF & Aspirin”. The selected cases would be the ones that were related directly to IVF cases. Results: Out of 219 articles, four studies evaluating the use of heparin and six studies evaluating the use of aspirin were included after all the other studies were eliminated based on exclusion criteria or didn’t match the inclusion criteria. All of the studies scored 6 or above out of 11 based on PEDro scale except for Siristadis et al which scored 4 out of 11. The outcome measures are implantation, clinical pregnancy, and live birth rate. However not all studies include all three measures. Conclusion: This systematic review concludes that the usage of heparin or aspirin for IVF treatment does not significantly improve the success rate of IVF treatment.