Please use this identifier to cite or link to this item:
Title: Pulmonary allograft versus Medtronic Freestyle valve in surgical pulmonary valve replacement for adults following correction of Tetralogy of Fallot or its variants.
Epworth Authors: Skillington, Peter
Menahem, Samuel
Larobina, Marco
Other Authors: Wijayarathne, Pasangi
Thuraisingam, Amalan
Grigg, Leeanne
Keywords: Medtronic Freestyle
Adult Congenital Heart Disease
Pulmonary Allograft Valve
Pulmonary Regurgitation
Pulmonary Stenosis
Pulmonary Valve Replacement
Tetralogy of Fallot
Cardiac Sciences Clinical Institute, Epworth HealthCare, Victoria, Australia
Issue Date: Sep-2019
Publisher: Sage
Citation: World J Pediatr Congenit Heart Surg. 2019 Sep;10(5):543-551
Abstract: Background: Following corrective surgery in infancy/childhood for tetralogy of Fallot (TOF) or its variants, patients may eventually require pulmonary valve replacement (PVR). Debate remains over which valve is best. We compared outcomes of the Medtronic Freestyle valve with that of the pulmonary allograft valve following PVR. Methods: A retrospective study was undertaken from a single surgical practice of adult patients undergoing elective PVR between April 1993 and March 2017. The choice of valve was at the surgeon's discretion. There was a trend toward the almost exclusive use of the more readily available Medtronic Freestyle valve since 2008. Results: One hundred fifty consecutive patients undergoing 152 elective PVRs were reviewed. Their mean age was 33.8 years. Ninety-four patients had a Medtronic Freestyle valve, while 58 had a pulmonary allograft valve. There were no operative or 30-day mortality. The freedom from reintervention at 5 and 10 years was 98% and 98% for the pulmonary allograft and 99% and 89% for the Medtronic Freestyle. There was no significant difference in the rate of reintervention, though this was colored by higher pulmonary gradients across the Medtronic Freestyle despite its shorter follow-up. Conclusions: Pulmonary valve replacement following previous surgical repair of TOF or its variants was found to be safe with no significant differences in mortality or reintervention between either valve. Although the Medtronic Freestyle valve had a greater tendency toward pulmonary stenosis, additional follow-up is needed to further document its long-term outcomes.
DOI: 10.1177/2150135119859853
PubMed URL:
ISSN: 2150-136X
Journal Title: World Journal for Pediatric and Congenital Heart Surgery
Type: Journal Article
Affiliated Organisations: Melbourne Medical School, University of Melbourne, Melbourne, Victoria, Australia
Department of Cardiothoracic Surgery, Royal Melbourne Hospital, Melbourne, Victoria, Australia
Department of Cardiothoracic Surgery, Melbourne Private Hospital, Parkville, Victoria, Australia
School of Clinical Sciences, Monash Health, Monash University, Clayton, Victoria, Australia
Department of Cardiology, Royal Melbourne Hospital, Melbourne, Victoria, Australia
Department of Cardiology, Melbourne Private Hospital, Melbourne, Victoria, Australia.
Type of Clinical Study or Trial: Retrospective studies
Appears in Collections:Cardiac Sciences

Files in This Item:
There are no files associated with this item.

Items in Epworth are protected by copyright, with all rights reserved, unless otherwise indicated.