Lateral lumbar interbody fusion – outcomes, complications and fusion rates with recombinant human bone morphogenetic protein-2.

Abstract

Direct lateral transpsoas retroperitoneal technique indicated for degenerative disc disease, disc herniation, spinal stenosis, deformity. Benefits: minimally invasive, large interbody cage for graft material, indirect neural decompression. Concerns: approach-related neuropraxia, visceral & vascular injury, safety at L4/5 rhBMP-2 boasts high fusion rates but is controversial around cost and potential adverse outcomes. Aims: 1.Report a consecutive series of patients undergoing LLIF with an emphasis on the clinical outcomes, fusion rates, and complication profile in particular neurological complications and complications occurring at L4/5 2.Report the use of rhBMP-2 in LLIF with an emphasis on the fusion rates and any adverse outcomes associated with its use.