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Title: A pilot study of fMRI targeted rTMS for obsessive compulsive disorder.
Epworth Authors: Fitzgerald, Paul
Hoy, Kate
Other Authors: Segrave, Rebecca
Fornito, Alex
Harrison, Ben
Keywords: Repetitive Transcranial Magnetic Stimulation
Obsessive Compulsive Disorder
Epworth Centre for Innovation in Mental Health, Epworth Healthcare and Monash University Department of Psychiatry, Victoria, Australia
Epworth Rehabilitation, Mental Health and Chronic Pain Clinical Institute, Epworth HealthCare, Victoria, Australia
Issue Date: Mar-2022
Publisher: Elsevier
Citation: Brain Stimul . Mar-Apr 2022;15(2):483-484
Abstract: Obsessive compulsive disorder (OCD) is a relatively common disorder, with a lifetime prevalence of 2–3% [1]. Morbidity arising from this chronic condition is extremely high and often leads to significant impairment in affected individuals [2,3]. Neuroimaging studies have implicated dysfunction in frontostriatal circuitry in the pathophysiology of OCD [4], showing that there is abnormal resting activity and functional connectivity of the orbitofrontal cortex, the anterior cingulate cortex (ACC), medial prefrontal cortex (PFC) and the caudate nucleus in people living with OCD. Repetitive transcranial magnetic stimulation (rTMS) it is increasingly being investigated as a potential therapeutic option for treatment resistant OCD with one form of treatment, deep TMS, now approved for clinical use in the US.
DOI: 10.1016/j.brs.2022.02.019
PubMed URL:
ISSN: 1935-861X
Journal Title: Brain Stimulation
Type: Letter
Affiliated Organisations: Turner Institute for Brain and Mental Health, School of Psychological Sciences, Monash University, Clayton, Melbourne, Victoria, Australia
Monash Biomedical Imaging, Monash University, Clayton, Melbourne, Victoria, Australia.
Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne, Parkville, Victoria, 3010, Australi
Appears in Collections:Mental Health

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