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Title: Therapy influences goal attainment following botulinum neurotoxin injection for focal spasticity in adults with neurological conditions.
Epworth Authors: Moore, Elizabeth
Olver, John
Williams, Gavin
McKenzie, Dean
Other Authors: Bryant, Adam
Keywords: Spasticity
Botulinum Toxin
Focal Spasticity
Therapeutic Outcome
Goal Attainment Scaling
Therapy Adherence
Rehabilitation, Mental Health and Chronic Pain Clinical Institute, Epworth HealthCare, Victoria, Australia
Epworth Monash Rehabilitation Unit (EMReM), Epworth HealthCare, Richmond, Victoria, Australia.
Issue Date: May-2018
Publisher: Taylor & Francis
Citation: Brain Inj. 2018 May 2:1-9
Abstract: OBJECTIVE: To determine whether therapy influenced goal attainment following botulinum toxin (BoNT-A) injection for focal spasticity in adults with neurological conditions. METHODS: A prospective observational cohort study conducted in a large metropolitan spasticity clinic on adults with focal spasticity of any origin. Participants were provided with a therapy programme, designed to maximise therapeutic outcome. The primary outcome measure was Goal Attainment Scaling. To measure adherence, participants completed a therapy-recording tool each day. Goal attainment, and the rate of adherence to the therapy programme, was evaluated after 10 weeks. RESULTS: Active indications for BoNT-A treatment made up the majority of the goals (80.30%). Goals were achieved in 43/76 cases (56.60%; 95% CI = 42.40 to 69.80%). Therapy adherence was associated with significantly greater goal attainment (OR = 1.02, p = 0.03, 95% CI = 1.00 to 1.04). Greater adherence to therapy increased the odds of goal achievement for active indications but not for passive indications, suggesting a possible statistical interaction between the indication for injection and adherence to therapy (p < 0.01). CONCLUSION: Therapy adherence was associated with greater goal attainment. Active indications for BoNT-A were more reliant on adherence to prescribed therapy programmes than passive indications, although further investigation is required.
DOI: 10.1080/02699052.2018.1469044
PubMed URL:
ISSN: 0269-9052
Journal Title: Brain Injury
Type: Journal Article
Affiliated Organisations: Physiotherapy Department , The University of Melbourne , Melbourne , Australia.
Rehabilitation Medicine , Monash University , Melbourne , Australia.
Department of Epidemiology and Preventive Medicine , Monash University , Melbourne , Australia.
Type of Clinical Study or Trial: Prospective Observational Study
Appears in Collections:Neurosciences

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