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Title: | The role of surgical excision for the Krukenberg tumour: A case report. |
Epworth Authors: | Ong, Eugene |
Other Authors: | Lam, David |
Keywords: | Krukenberg Tumour KT Colorectal Cancer Cytoreductive Surgery CRS Carcinomatosis Peritoneii Peritoneal Metastatic Disease Intraperitoneal Chemotherapy Carcinoma Ovary Metastatic Colorectal Cancer Prognosis Metachronous Right Ovarian KT Contralateral Ovary Transcoloemic Dissemination Ovarian Metastasis Clinical Features Chemo-Resistance Concomitant Symptom Control Survival Benefit General Surgery and Gastroenterology Clinical Institute, Epworth HealthCare, Victoria, Australia |
Issue Date: | Jul-2017 |
Publisher: | Elsevier |
Citation: | Int J Surg Case Rep. 2017 Jul 25;38:185-188 |
Abstract: | INTRODUCTION: Krukenberg tumour (KT), which represents carcinoma in the ovary, is an uncommon manifestation of metastatic colorectal cancer. It is associated with poor prognosis and a high incidence of peritoneal metastatic disease. PRESENTATION OF CASE: The authors present a case of a 51-year-old female who had a symptomatic, metachronous right ovarian KT diagnosed 12 months after her initial resection. Surgery was performed to excise the 23cm tumour as well as the contralateral ovary and isolated peritoneal disease, with an R0 resection achieved. DISCUSSION: KT from colorectal origin behave differently to non-ovarian colorectal metastases, with features suggestive of transcoloemic dissemination. Surgical removal of isolated ovarian metastasis without peritoneal involvement is associated with improved outcomes. Treatment with cytoreductive surgery and heated intraperitoneal chemotherapy offers promise for patients with KT and concominant peritoneal involvement. CONCLUSION: This case is illustrative of the clinical features of KT including its chemo-resistance and concomitant carcinomatosis peritoneii. Cytoreductive surgery for KT provides symptom control and confers survival benefit in selected patients. |
URI: | http://hdl.handle.net/11434/1242 |
DOI: | 10.1016/j.ijscr.2017.07.046 |
URL: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540708/ |
PubMed URL: | https://www.ncbi.nlm.nih.gov/pubmed/28772202 |
ISSN: | 2210-2612 |
Journal Title: | International Journal of Surgery Case Reports |
Type: | Journal Article |
Affiliated Organisations: | Department of Colorectal Surgery, St Vincent's Hospital Melbourne, 41 Victoria Street, Fitzroy, VIC 3065, Australia. |
Type of Clinical Study or Trial: | Case Reports |
Appears in Collections: | Cancer Services General Surgery and Gastroenterology |
Files in This Item:
File | Description | Size | Format | |
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Lam & Ong 2017.pdf | 764.08 kB | Adobe PDF | View/Open |
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