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dc.contributor.authorZargar, Homayoun-
dc.contributor.authorMoon, Daniel-
dc.contributor.authorFrydenberg, Mark-
dc.contributor.authorCostello, Anthony-
dc.contributor.authorBotti, Mari-
dc.identifier.citationJul-2016, Poster 58en_US
dc.description.abstractIntroduction/Background: To prospectively and independently assess real world outcomes of Australian men's urinary and sexual function following retropubic (RRP), laparoscopic (LRP) and robotic assisted (RARP) radical prostatectomy surgery for localized prostate cancer. Methods: From 2009 to 2012 men with localized prostate cancer undergoing surgery by one of the fourteen urologists working across eight private-sector sites were included. Patients were consented and data was collected by self-reported questionnaires prospectively at 3,6,12,18 and 24 months by independent researchers. Urinary and sexual function data were obtained using EPIC, SHIM and IPSS questionnaires. Results: Overall 1005 men were recruited (participation rate of 79.2%), with 836 men having completed surveys at each follow-up. At 24 months follow-up the median EPIC urinary and sexual summary scores were at 95.6 and 47.4% of baseline respectively. The rate of erectile function preservation at 24 months in men with good erectile function preoperatively (SHIM≥ 20) was 27% for the entire cohort. On multivariable cox regression model (including age, Gleason score, prostate volume, preoperative SHIM score, surgical modality), age (OR 0.94 95% CI (0.91-0.97); p-0.001), preoperative erectile function (OR 1.26 95% CI (1.14-.41); p<0.001) and laparoscopic approach (OR 0.23 95% CI (0.09-0.60); p=0.002 were predictors of erectile function at 24 months. Conclusions: Surgical therapy for localized prostate cancer provides excellent long-term urinary function as measured by EPIC urinary summary score in our series. Long-term sexual function was less preserved as demonstrated by 24 months EPIC sexual summary score. The rate of sexual function preservation for men with good pre-existing sexual function treated by surgical therapy in this real world prospective independently collected community based study is far lower than previously reported by tertiary referral centres. The impact of surgeon's training and experience are likely to be important determiners of long-term sexual functions and will be addressed in the future studies.en_US
dc.subjectProstate Canceren_US
dc.subjectRobotic assisteden_US
dc.subjectRadial Prostatectomy Surgeryen_US
dc.subjectLong Term Sexual Functionen_US
dc.subjectProstatic Neoplasmsen_US
dc.subjectUrinary Functionen_US
dc.subjectErectile Functionen_US
dc.subjectPoster 58en_US
dc.subjectEpworth/Deakin Centre for Clinical Nursing Research, Deakin University, Melbourne, Australia.en_US
dc.subjectEpworth Prostate Centre, Epworth HealthCare, Victoria, Australia.en_US
dc.subject​UroRenal & Vascular Clinical Institute, Epworth HealthCare, Victoria, Australia.en_US
dc.titleProspective longitudunal comparative study of long-term urinary and sexual function after primary surgical treatment for localized prostate cancer.en_US
dc.typeConference Posteren_US
dc.description.affiliatesDepartments of Urology and Surgery, Royal Melbourne Hosiptal, Parkville, VIC, Australia.en_US
dc.description.affiliatesPeter MacCallum Cancer Centre, Melbourne VIC, Australia.en_US
dc.description.affiliatesDepartment of Surgery, Deaprtment of Urology, Monash University.en_US
dc.type.studyortrialCohort Studyen_US
dc.description.conferencenameEpworth Research Institute Research Week 2016en_US
dc.description.conferencelocationEpworth, Richmond, Victoria, Australia.en_US
Appears in Collections:Cancer Services

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