Please use this identifier to cite or link to this item: http://hdl.handle.net/11434/947
Title: Re: Marco Borghesi, Hashim Ahmed, Robert Nam, et al. Complications after systematic, random, and image-guided prostate biopsy.
Epworth Authors: Grummet, Jeremy
Moon, Daniel
Other Authors: Pepdjonovic, Lana
Keywords: Complications
Hospitalisation
Infection
MRI-Guided Biopsy
Mortality
Sepsis
Transrectal Prostate Biopsy
Fluoroquinolone Resistance
Sterility
Prophylaxis
UroRenal, Vascular Clinical Institute, Epworth HealthCare, Victoria, Australia
Australian Prostate Cancer Research Centre, Epworth HealthCare, Victoria, Australia.
Issue Date: 2016
Publisher: Elsevier
Citation: Vol.70, 29 Oct. 2016
Abstract: In a recent review, Borghesi et al concluded that sepsis is the most troublesome complication following transrectal prostate biopsy and that its incidence continues to increase due to the ongoing rise of fluoroquinolone resistance. We believe the time is nigh to abandon the transrectal approach. In performing transrectal biopsy, we forsake basic surgical principles of sterility for the convenience of this approach, using antibiotics as a substitute for hygiene. Quinolones are recommended as standard prophylaxis, but are losing their effect. The US Center for Disease Control states that “use of antibiotics is the single most important factor leading to resistance around the world”. The World Health Organization implores us to reduce unnecessary antibiotic usage for fear of creating a postantibiotic era. Proposed preventative solutions to prostate biopsy sepsis involving multidrug or broader spectrum prophylaxis are therefore in direct contravention of these warnings and are irresponsible. Continues.
URI: http://hdl.handle.net/11434/947
DOI: doi.org/10.1016/j.eururo.2016.08.004
PubMed URL: https://www.ncbi.nlm.nih.gov/pubmed/27543165
ISSN: 0302-2838
Journal Title: European Urology
Type: Letter
Affiliated Organisations: Department of Urology, Alfred Hospital, Melbourne, Victoria, Australia
Division of Cancer Surgery, University of Melbourne, Peter MacCallum Cancer Centre, Melbourne, Victoria 3000, Australia
Appears in Collections:Cancer Services
UroRenal, Vascular
Epworth Prostate Centre

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