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|Title:||Choice of approach does not affect clinical and radiologic outcomes: a comparative cohort of patients having anterior lumbar interbody fusion and patients having lateral lumbar interbody fusion at 24 months.|
|Epworth Authors:||Malham, Gregory|
|Other Authors:||Parker, Rhiannon|
Chow, F. Y.
Degenerative Disc Disease
Oswestry Disability Index
Physical Component Score
Mental Component Score
Anterior Lumbar Interbody Fusion
Lateral Lumbar Interbody Fusion
Neurosciences Clinical Institute, Epworth HealthCare, Victoria, Australia
|Citation:||Global Spine J. 2016 Aug;6(5):472-81|
|Abstract:||STUDY DESIGN: Retrospective analysis of prospectively collected registry data. OBJECTIVE: This study aimed to compare the clinical and radiologic outcomes between comparative cohorts of patients having anterior lumbar interbody fusion (ALIF) and patients having lateral lumbar interbody fusion (LLIF). METHODS: Ninety consecutive patients were treated by a single surgeon with either ALIF (n = 50) or LLIF (n = 40). Inclusion criteria were patients age 45 to 70 years with degenerative disk disease or grade 1 to 2 spondylolisthesis and single-level pathology from L1 to S1. Patient-reported outcome measures included pain (visual analog scale), disability (Oswestry Disability Index [ODI]), and quality of life (Short Form 36 physical component score [PCS] and mental component scores [MCS]). Assessment of fusion and measurement of lordosis and posterior disk height were performed on computed tomography scans. RESULTS: At 24 months, patients having ALIF had significant improvements in back (64%) and leg (65%) pain and ODI (60%), PCS (44%), and MCS (26%; p < 0.05) scores. Patients having LLIF had significant improvements in back (56%) and leg (57%) pain and ODI (52%), PCS (48%), and MCS (12%; p < 0.05) scores. Fourteen complications occurred in the ALIF group, and in the LLIF group, there were 17 complications (p > 0.05). The fusion rate was 100% for ALIF and 95% for LLIF (p = 0.1948). ALIF added ∼6 degrees of lordosis and 3 mm of height, primarily measured at L5-S1, and LLIF added ∼3 degrees of lordosis and 2 mm of height between L1 to L5. Mean follow-up was 34.1 months. CONCLUSIONS: In comparative cohorts of patients having ALIF and patients having LLIF at 24 months postoperatively, there were no significant differences in clinical outcomes, complication rates, or fusion rates.|
|Journal Title:||Global Spine Journal|
|Affiliated Organisations:||Neurosurgery Department, Macquarie University, Sydney, New South Wales, Australia.|
|Type of Clinical Study or Trial:||Retrospective studies|
|Appears in Collections:||Neurosciences|
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