Please use this identifier to cite or link to this item: http://hdl.handle.net/11434/733
Title: Factors affecting the risk of deep venous occlusion after ultrasound-guided sclerotherapy for varicose veins.
Epworth Authors: Myers, Ken
Other Authors: Jolley, D.
Keywords: Sclerosing Solutions
Sclerotherapy
Ultrasonography
Varicose Veins
Venous Thrombosis
Deep Vein Thrombosis
Deep Venous Occlusion
DVO
Ultrasound Guided Sclerotherapy
UGS
Victoria Vein Clinic, Epworth HealthCare, Australia
Urorenal and Vascular Clinical Institute, Epworth HealthCare
Issue Date: Nov-2008
Publisher: Elsevier
Citation: Eur J Vasc Endovasc Surg. 2008 Nov;36(5):602-5
Abstract: OBJECTIVE: To determine which covariates predisposed to deep venous occlusion (DVO) after ultrasound-guided sclerotherapy (UGS) for varicose veins. DESIGN: Ultrasound scans before and at 3 to 7 days after UGS to detect post-procedure deep venous occlusion. MATERIALS: A consecutive series of 1931 treatment sessions in 852 patients treated by a technique for UGS. METHODS: Ultrasound examination of the full length of axial deep veins above and below knee before and soon after every procedure. Crude chi(2) analysis of all covariates allowed selection of those that showed apparent significant influence. Logistic regression analysis of these then determined which independently predisposed to post-procedure deep venous occlusion. RESULTS: Deep venous occlusion was only observed after UGS using foamed sclerosant and occurred following 28 treatment sessions. No significant difference for risk of deep venous occlusion was observed for patient characteristics or which veins were treated. Logistic regression analysis showed significant independent increased risk in a limb from using highly diluted or undiluted sclerosant (OR 0.55; 95% CI 0.19 to 1.59 for 0.6-1.0% solution, OR 10.45; 95% CI 3.12 to 34.99 for 2-2.3% and OR 0.36; 95% CI 0.07 to 1.74 for 3% solution), treating veins >or=5mm diameter (OR 3.70; 95% CI 1.23 to 11.13) and injecting >or=10 ml of foamed sclerosant for a limb (OR 3.64; 95% CI 1.21 to 10.90). CONCLUSIONS: The risk of deep venous occlusion after UGS in this series was lower when using highly diluted or undiluted sclerosant, when treating veins less than 5mm in diameter and when restricting the volume of foam injected to less than 10 ml.
URI: http://hdl.handle.net/11434/733
DOI: 10.1016/j.ejvs.2008.06.026
URL: http://www.sciencedirect.com/science/article/pii/S107858840800364X
PubMed URL: http://www.ncbi.nlm.nih.gov/pubmed/18718772
ISSN: 1078-5884
1532-2165
Journal Title: European Journal of Vascular and Endovascular Surgery
Type: Journal Article
Type of Clinical Study or Trial: Cohort Study
Appears in Collections:Diagnostic Services
UroRenal, Vascular

Files in This Item:
File Description SizeFormat 
Factors Affecting the Risk of Deep Venous Occlusion.pdf99.94 kBAdobe PDFView/Open


Items in EKB are protected by copyright, with all rights reserved, unless otherwise indicated.