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Title: Androgenetic alopecia. Modelling progression and regrowth.
Epworth Authors: Sinclair, Rodney
Keywords: Balding
Androgenetic Alopecia
Female Pattern Baldness
Male Patern Baldness
Hair Cycle
Hair Follicle Miniaturization
Hair Thinning
Head & Neck Clinical Institute, Epworth HealthCare, Victoria, Australia
Chair of Dermatology, Epworth HealthCare, Victoria, Australia
Issue Date: Jun-2016
Publisher: Wiley
Citation: Exp Dermatol. 2016 Jun;25(6)
Abstract: Androgenetic alopecia (AGA) produces the phenotypes of male pattern hair loss and female pattern hair loss. The pathogenesis of AGA involves hair follicle miniaturization and changes to the hair cycle. Hair follicle miniaturization involves conversion of terminal hairs into secondary vellus hairs. This is recognized in scalp biopsies, unit area trichograms and phototrichograms as a reduction in the number of terminal hairs per cm2 and an increase in the number of vellus hairs per cm2.. In addition, a small reduction in the total number of hair follicles detectable on scalp biopsy occurs with advancing age. So, how can we incorporate these findings into our current model of the pathogenesis of androgenetic alopecia?
DOI: 10.1111/exd.13029
PubMed URL:
ISSN: 1600-0625
Journal Title: Experimental Dermatology
Type: Journal Article
Affiliated Organisations: Department of Dermatology, University of Melbourne, Melbourne, Vic., Australia
Appears in Collections:Head & Neck

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