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Title: Management of spasticity in moderate and severe traumatic brain injury: evaluation of clinical practice guidelines.
Authors: Olver, John
Other Authors: Pattuwage, Loyal
Martin, Caius
Lai, Francis
Piccenna, Loretta
Gruen, Russell
Bragge, Peter
Keywords: Brain Injury
Traumatic Brain Injury
Quality of Life
Clinical Practice Guidelines
Appraisal of Guidelines for Research and Evaluation II
Mental Health and Chronic Pain Clinical Institute, Epworth HealthCare, Victoria, Australia
Issue Date: Apr-2016
Publisher: Wolters Kluwer
Citation: J Head Trauma Rehabil. 2016 Apr 26
Abstract: INTRODUCTION: Moderate to severe traumatic brain injury (TBI) can result in development of spasticity, which adversely affects function and quality of life. Given the foundation of optimal clinical practice is use of the best available evidence, we aimed to identify, describe, and evaluate methodological quality of evidence-based spasticity clinical practice guidelines (CPGs). METHODS: A comprehensive search for CPGs encompassed electronic databases and online sources. Eligible CPGs were evaluated using the validated Appraisal of Guidelines for Research and Evaluation II (AGREE II) instrument. RESULTS: Five CPGs were eligible for review; 2 were specific to acquired brain injury and 1 to TBI. The 3 brain injury-specific CPGs contained 423 recommendations overall, but only 8 spasticity recommendations. On the basis of AGREE appraisals, all CPGs performed well in the areas of reporting scope and purpose; clearly presenting recommendations; including various stakeholders in the CPG development process; and reporting conflict of interest. However, only one CPG performed adequately on describing facilitators and barriers to implementation, advice, and tools on how to implement recommendations and provision of audit criteria. Intraclass correlation coefficient (ICC) for agreement between raters showed high agreement (ICC > 0.80) for most guidelines. CONCLUSION: Given the unique etiological features and treatment challenges associated with managing spasticity after TBI, more TBI-specific spasticity CPGs are required. These should incorporate information on the facilitators and barriers to implementation, advice on implementing recommendations, and audit criteria.
DOI: 10.1097/HTR.0000000000000234
PubMed URL:
ISSN: 0885-9701
Journal Title: The Journal of Head Trauma Rehabilitation
Type: Journal Article
Affiliated Organisations: National Trauma Research Institute, Monash University, Alfred Hospital, Melbourne, Victoria, Australia
Monash Health, Melbourne, Victoria, Australia
School of Allied Health, La Trobe University, Melbourne, Victoria, Australia
Nanyang Technological University, Singapore
Monash Sustainability Institute, Monash University, Melbourne, Victoria, Australia
Type of Clinical Study or Trial: Review
Appears in Collections:Neurosciences

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