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Title: Verbal fluency, clustering and switching in patients with psychosis following traumatic brain injury (PFTBI).
Epworth Authors: Ponsford, Jennie
Johnston, Lisa
Other Authors: Batty, Rachel
Francis, Andrew
Thomas, Neil
Hopwood, Malcolm
Rossell, Susan
Keywords: Verbal Fluency Disorders
Speech Disorders
Head Injuries
Trauma, Head
Brain Injuries
Trauma, Brain
Traumatic Brain Injury
Psychotic Disorders
Monash-Epworth Rehabilitation Research Centre, Richmond, Victoria, Australia
Issue Date: Jun-2015
Publisher: Elsevier
Citation: Psychiatry Research 2015 June 30, Volume 227, Issues 2–3, Pages 152–159
Abstract: Verbal fluency in patients with psychosis following traumatic brain injury (PFTBI) has been reported as comparable to healthy participants. This finding is counterintuitive given the prominent fluency impairments demonstrated post-traumatic brain injury (TBI) and in psychotic disorders, e.g. schizophrenia. We investigated phonemic (executive) fluency (3 letters: ‘F’ ‘A’ and ‘S’), and semantic fluency (1 category: fruits and/or vegetables) in four matched groups; PFTBI (N=10), TBI (N=10), schizophrenia (N=23), and healthy controls (N=23). Words produced (minus perseverations and errors), and clustering and switching scores were compared for the two fluency types across the groups. The results confirmed that PFTBI patients do show impaired fluency, aligned with existing evidence in TBI and schizophrenia. PFTBI patients produced the least amount of words on the phonemic fluency (‘A’) trial and total score, and demonstrated reduced switching on both phonemic and semantic tasks. No significant differences in clustering performance were found. Importantly, the pattern of results suggested that PFTBI patients share deficits with their brain-injured (primarily executive), and psychotic (executive and semantic), counterparts, and that these are exacerbated by their dual-diagnosis. These findings add to a very limited literature by providing novel evidence of the nature of fluency impairments in dually-diagnosed PFTBI.
Description: Highlights •PFTBI patients show impaired executive and semantic fluency. •PFTBI deficits appear to be shared with their brain-injured, and psychotic, counterparts. • We are first to demonstrate the value of face-to-face assessments of PFTBI patients. • We are first to match PFTBI cases with TBI and schizophrenia patient controls during recruitment. • We are first to assess PFTBI and matched patient groups using a psychometrically sound battery.
DOI: 10.1016/j.psychres.2015.03.040
PubMed URL:
ISSN: 0165-1781
Journal Title: Psychiatry Research
Type: Journal Article
Affiliated Organisations: Brain and Psychological Sciences Research Centre (BPsyC), Faculty of Health, Arts and Design, Swinburne University of Technology, Melbourne, Victoria, Australia
Monash-Alfred Psychiatry Research Centre (MAPrc), Melbourne, Victoria, Australia
RMIT University, Bundoora, Victoria, Australia
University of Melbourne Department of Psychiatry, Albert Road Clinic, Melbourne, Victoria, Australia
Psychiatry, St Vincent׳s Hospital, Melbourne, Australia
Neuroimaging Facility, Brain and Psychological Sciences Research Centre, Hawthorn, Victoria 3122, Australia
Type of Clinical Study or Trial: Case Control Studies
Appears in Collections:Neurosciences

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