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Title: Comparison of [11C]choline Positron Emission Tomography With T2- and Diffusion-Weighted Magnetic Resonance Imaging for Delineating Malignant Intraprostatic Lesions
Epworth Authors: O'Sullivan, Richard
Other Authors: Chang, Joe
Lim Loon, Daryl
Davis, Ian
Lee, Sze Ting
Hiew, Chee Yan
Esler, Stephen
Gong, Sylvia
Wada, Morikatsu
Clouston, David
Goh, Yin
Bolton, Damien
Scott, Andrew
Khoo, Vincent
Keywords: Imaging Modalities
Focal Therapies
[11C]choline positron emission tomography
Magnetic Resonance Imaging
Malignant Intraprostatic Lesions
Prostate Adenocarcinoma
Radical Prostatectomy
Healthcare Imaging, Epworth Hospital, Victoria, Australia
Healthcare Imaging, Epworth Hospital, Victoria, Australia
Issue Date: Jun-2015
Publisher: Elsevier
Citation: Int J Radiat Oncol Biol Phys. 2015 Jun 1;92(2):438-45.
Abstract: Novel imaging modalities can be used to define targets within the prostate to guide focal therapies, which can theoretically improve the therapeutic ratio compared to conventional whole-gland therapies. We used histopathological reference standards to compare [11C]choline positron emission tomography (PET) with magnetic resonance imaging (MRI) for delineating malignant intraprostatic lesions for guiding focal therapies. [11C]choline PET was found to be significantly more accurate than MRI.
DOI: 10.1016/j.ijrobp.2015.02.004
PubMed URL:
ISSN: 0360-3016
Journal Title: International Journal of Radiation Oncology, Biology, Physics
Type: Journal Article
Affiliated Organisations: Radiation Oncology Centre, Austin Health, Victoria, Australia
The University of Melbourne, Melbourne, Victoria, Australia
Monash University Eastern Health Clinical School, Victoria, Australia
Centre for PET, Austin Health, Victoria, Australia
Ludwig Institute for Cancer Research, Victoria, Australia
Department of Radiology, Austin Health, Victoria, Australia
Tissupath, Mt Waverley, Victoria, Australia
Diagnostic Imaging, Monash Health, Victoria, Australia
Department of Urology, Austin Health, Victoria, Australia
Royal Marsden Hospital, National Health Service Foundation Trust, London, United Kingdom
Type of Clinical Study or Trial: Cohort Study
Appears in Collections:Cancer Services
Radiation Oncology

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