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Title: FDG-PET/CT findings, the vital clue to rare diagnosis of herpes simplex virus lymphadenitis simulating Richter transformation.
Epworth Authors: Prince, Miles
Other Authors: Douglas, Abby
Atarod, Mohammad
Keywords: FDG-PET/CT Findings
Herpes Simplex Virus (HSV)
Richter Transformation
Chronic Lymphocytic Leukaemia (CLL)
Orolabial HSV
Mild Diffuse Splenic Uptake
Diagnostic Laparotomy
Retroperitoneal Lymph Nodes
Focal Necrotising Granulomatous Process
Histiocyte Debris
Oral Valaciclovir Therapy
HSV Lymphadenitis
B Symptoms
Central Photopenia
Epworth Centre for Immunotherapies and Snowdome Laboratories
Molecular Oncology and Cancer Immunology
Cancer Services Clinical Institute, Epworth HealthCare, Victoria, Australia
Issue Date: Jan-2019
Publisher: Elsevier
Citation: Pathology, 51(1), 102–104.
Abstract: Sir, A 55-year-old male born in Vietnam, with known chronic lymphocytic leukaemia (CLL) monitored without therapy, presented with new fevers, night sweats, loss of weight and retroperitoneal lymphadenopathy. He was subsequently diagnosed with herpes simplex virus (HSV) lymphadenitis based on histopathological findings. The patient denied any focal symptoms and had no localising signs to point to a source of fever.......
DOI: 10.1016/j.pathol.2018.08.016
PubMed URL:
ISSN: 0031-3025
Journal Title: Pathology
Type: Letter
Affiliated Organisations: Department of Infectious Diseases, Peter MacCallum Cancer Centre, Melbourne, Vic, Australia
Sir Peter MacCallum Department of Oncology, University of Melbourne, Melbourne, Vic, Australia
The National Centre for Infections in Cancer, Peter MacCallum Cancer Centre, Melbourne, Vic, Australia
Anatomical Pathology, Melbourne Pathology, Melbourne, Vic, Australia
Department of Haematology, Peter MacCallum Cancer Centre, Melbourne, Vic, Australia
Type of Clinical Study or Trial: Case Reports
Appears in Collections:Cancer Services

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