Please use this identifier to cite or link to this item: http://hdl.handle.net/11434/173
Title: Beyond goosebumps: does the arrector pili muscle have a role in hair loss?
Epworth Authors: Sinclair, Rodney
Rufaut, Nick
Jones, Leslie
Torkamani, Niloufar
Keywords: Androgenic Alopecia
Arrector Pili Muscle
Hair Loss
Alopecia
Thermoregulation
Connective Tissue
Hair Follicle
Regulation, Body Temperature
Temperature Regulation, Body
Body Temperature Regulation
Chair of Dermatology, Epworth HealthCare, Victoria, Australia
Head & Neck Clinical Institute, Epworth HealthCare, Victoria, Australia
Issue Date: Jul-2014
Citation: 2014 Jul; 6(3):88-94.
Abstract: The arrector pili muscle (APM) consists of a small band of smooth muscle that connects the hair follicle to the connective tissue of the basement membrane. The APM mediates thermoregulation by contracting to increase air-trapping, but was thought to be vestigial in humans. The APM attaches proximally to the hair follicle at the bulge, a known stem cell niche. Recent studies have been directed toward this muscle's possible role in maintaining the follicular integrity and stability. This review summarizes APM anatomy and physiology and then discusses the relationship between the follicular unit and the APM. The potential role of the APM in hair loss disorders is also described, and a model explaining APM changes in hair loss is proposed.
URI: http://hdl.handle.net/11434/173
DOI: 10.4103/0974-7753.139077
PubMed URL: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4158628/
ISSN: 0974-9241
0974-7753
Journal Title: International Journal of Trichology
Type: Journal Article
Affiliated Organisations: The University of Melbourne, Melbourne, Victoria, Australia
St Vincent's Hospital, Melbourne, Victoria, Australia
Appears in Collections:Head & Neck
Dermatology

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