Please use this identifier to cite or link to this item:
|Title:||Short-term outcome of emergency colorectal cancer surgery: results from Bi-National Colorectal Cancer Audit.|
|Epworth Authors:||Sitzler, Paul|
|Other Authors:||Kong, J.|
Bi-National Colorectal Cancer Audit Database
Length of Stay
Logistic Regression Analysis
Independent Predictors for Inpatient Mortality
Bootstrap Re-sampling Method
American Society Anesthesiologists Score
General Surgery and Gastroenterology Clinical Institute, Epworth HealthCare, Victoria, Australia
Cancer Services Clinical Institute, Epworth HealthCare, Victoria, Australia
|Citation:||Int J Colorectal Dis. 2018 Sep 30.|
|Abstract:||BACKGROUNDS: A significant number of patients with colorectal cancer will have an emergency presentation requiring surgery. This study aims to evaluate short-term outcomes for patients undergoing emergency colorectal cancer surgery in Australasia. METHODS: All consecutive CRC from the Bi-National Colorectal Cancer Audit Database was interrogated from 2007 to 2016. Short-term outcomes including length of stay, complication rate and mortality rate were compared between the emergency and elective groups. Logistic regression analysis was performed to identify independent predictors for inpatient mortality. A predictive model for inpatient mortality was constructed using these variables, and its accuracy was then validated by the Bootstrap re-sampling method. RESULTS: Of 15,676 colorectal cancer cases identified, 13.6% were emergency cases. The emergency group had a higher rate of surgical and medical complications (26.7% vs 22.6%, p < 0.001; 22.8 vs 13.8%, p < 0.001, respectively). Higher inpatient mortality rate was also observed in the emergency group (3.4% vs 2.6%, p = 0.023). Independent predictors for inpatient survival included age, American Society Anaesthesiologists score, emergency surgery and tumour stage. In addition, postoperative complications such as anastomotic leak (odds ratio [OR] 3.78, p < 0.001), sepsis (OR 2.85, p < 0.001) and medical complications (OR 13.88, p < 0.001) had a significant impact in survival in the emergency group. Receiver operating characteristics curve for inpatient mortality was 0.913. CONCLUSION: Emergency colorectal cancer surgery carries significant morbidity and mortality. Recognition of the increasing rate of postoperative complications may help minimise the detrimental impact of this event on overall outcomes.|
|Journal Title:||International Journal of Colorectal Disease|
|Affiliated Organisations:||Division of Cancer Surgery, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia|
Cancer Research Program, School of Public Health & Preventive Medicine, Faculty of Medicine, Monash University, Monash, Melbourne, VIC, Australia.
Epworth Healthcare, Melbourne, VIC, Australia.
|Type of Clinical Study or Trial:||Audit|
|Appears in Collections:||Cancer Services|
General Surgery and Gastroenterology
Files in This Item:
There are no files associated with this item.
Items in EKB are protected by copyright, with all rights reserved, unless otherwise indicated.