Please use this identifier to cite or link to this item: http://hdl.handle.net/11434/1246
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dc.contributor.authorPonsford, Jennie-
dc.contributor.otherGabbe, Belinda-
dc.contributor.otherSimpson, Pamela-
dc.contributor.otherCameron, Peter-
dc.contributor.otherLyons, Ronan-
dc.contributor.otherCollie, Alex-
dc.contributor.otherFitzgerald, Mark-
dc.contributor.otherJudson, Rodney-
dc.contributor.otherTeague, Warwick-
dc.contributor.otherBraaf, Sandra-
dc.contributor.otherNunn, Andrew-
dc.contributor.otherAmeratunga, Shanthi-
dc.contributor.otherHarrison, James-
dc.date.accessioned2017-09-28T01:49:36Z-
dc.date.available2017-09-28T01:49:36Z-
dc.date.issued2014-07-
dc.identifier.citationPLoS Med. 2017 Jul 5;14(7):e1002322en_US
dc.identifier.issn1549-1277en_US
dc.identifier.issn1549-1676en_US
dc.identifier.urihttp://hdl.handle.net/11434/1246-
dc.description.abstractBACKGROUND: Improved understanding of the quality of survival of patients is crucial in evaluating trauma care, understanding recovery patterns and timeframes, and informing healthcare, social, and disability service provision. We aimed to describe the longer-term health status of seriously injured patients, identify predictors of outcome, and establish recovery trajectories by population characteristics. METHODS AND FINDINGS: A population-based, prospective cohort study using the Victorian State Trauma Registry (VSTR) was undertaken. We followed up 2,757 adult patients, injured between July 2011 and June 2012, through deaths registry linkage and telephone interview at 6-, 12-, 24-, and 36-months postinjury. The 3-level EuroQol 5 dimensions questionnaire (EQ-5D-3L) was collected, and mixed-effects regression modelling was used to identify predictors of outcome, and recovery trajectories, for the EQ-5D-3L items and summary score. Mean (SD) age of participants was 50.8 (21.6) years, and 72% were male. Twelve percent (n = 333) died during their hospital stay, 8.1% (n = 222) of patients died postdischarge, and 155 (7.0%) were known to have survived to 36-months postinjury but were lost to follow-up at all time points. The prevalence of reporting problems at 36-months postinjury was 37% for mobility, 21% for self-care, 47% for usual activities, 50% for pain/discomfort, and 41% for anxiety/depression. Continued improvement to 36-months postinjury was only present for the usual activities item; the adjusted relative risk (ARR) of reporting problems decreased from 6 to 12 (ARR 0.87, 95% CI: 0.83-0.90), 12 to 24 (ARR 0.94, 95% CI: 0.90-0.98), and 24 to 36 months (ARR 0.95, 95% CI: 0.95-0.99). The risk of reporting problems with pain or discomfort increased from 24- to 36-months postinjury (ARR 1.06, 95% CI: 1.01, 1.12). While loss to follow-up was low, there was responder bias with patients injured in intentional events, younger, and less seriously injured patients less likely to participate; therefore, these patient subgroups were underrepresented in the study findings. CONCLUSIONS: The prevalence of ongoing problems at 3-years postinjury is high, confirming that serious injury is frequently a chronic disorder. These findings have implications for trauma system design. Investment in interventions to reduce the longer-term impact of injuries is needed, and greater investment in primary prevention is needed.en_US
dc.publisherPublic Library of Scienceen_US
dc.relation.urihttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC5497942/pdf/pmed.1002322.pdf-
dc.subjectTrauma Careen_US
dc.subjectVictorian State Trauma Registryen_US
dc.subjectVSTRen_US
dc.subject3-Level EuroQol 5 Dimensions Questionnaireen_US
dc.subjectEQ-5D-3Len_US
dc.subjectTrauma System Designen_US
dc.subjectPopulation Based Designen_US
dc.subjectAdjusted Relative Risken_US
dc.subjectARRen_US
dc.subjectQuality of Survivalen_US
dc.subjectRecovery Patternsen_US
dc.subjectRecovery Timeframesen_US
dc.subjectPredictors of Outcomeen_US
dc.subjectRecovery Trajectoriesen_US
dc.subjectOrganised Trauma Systemsen_US
dc.subjectRESTORE studyen_US
dc.subjectREcovery after Serious Trauma Outcomes, Resource use, and patient Experiencesen_US
dc.subjectRehabilitation, Mental Health and Chronic Pain Clinical Institute, Epworth healthCare, Victoria, Australiaen_US
dc.subjectMonash-Epworth Rehabilitation Research Centre, Melbourne, Victoria, Australia.en_US
dc.titleLong-term health status and trajectories of seriously injured patients: A population-based longitudinal study.en_US
dc.typeJournal Articleen_US
dc.identifier.doidoi: 10.1371/journal.pmed.1002322en_US
dc.identifier.journaltitlePLoS Medicineen_US
dc.description.pubmedurihttps://www.ncbi.nlm.nih.gov/pubmed/28678814en_US
dc.description.affiliatesSchool of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia.en_US
dc.description.affiliatesFarr Institute, Swansea University Medical School, Swansea University, Swansea, United Kingdom.en_US
dc.description.affiliatesEmergency and Trauma Centre, The Alfred, Melbourne, Victoria, Australia.en_US
dc.description.affiliatesSchool of Psychological Sciences, Monash University, Melbourne, Victoria, Australia.en_US
dc.description.affiliatesInsurance Work and Health Group, Faculty of Medicine Nursing and Health Sciences, Monash University, Melbourne, Victoria, Australia.en_US
dc.description.affiliatesTrauma Service, The Alfred, Melbourne, Victoria, Australia.en_US
dc.description.affiliatesDepartment of Surgery, Monash University, Melbourne, Victoria, Australia.en_US
dc.description.affiliatesTrauma Service, Royal Melbourne Hospital, Parkville, Victoria, Australia.en_US
dc.description.affiliatesTrauma Service, The Royal Children's Hospital, Melbourne, Victoria, Australia.en_US
dc.description.affiliatesDepartment of Paediatrics, University of Melbourne, Melbourne, Victoria, Australia.en_US
dc.description.affiliatesSurgical Research Group, Murdoch Children's Research Institute, Melbourne, Victoria, Australia.en_US
dc.description.affiliatesVictorian Spinal Cord Service, Austin Health, Heidelberg, Victoria, Australia.en_US
dc.description.affiliatesSection of Epidemiology and Biostatistics, School of Population Health, University of Auckland, Auckland, New Zealand.en_US
dc.description.affiliatesResearch Centre for Injury Studies, Flinders University, Adelaide, South Australia, Australia.en_US
dc.type.studyortrialProspective Cohort Studyen_US
dc.type.contenttypeTexten_US
Appears in Collections:Critical Care
Rehabilitation

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