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Title: Prevalence of excessive tearing in women with early breast cancer receiving adjuvant Docetaxel-based chemotherapy.
Authors: De Boer, Richard
Other Authors: Chan, Arlene
Su, Charles
Gajdatsy, Adam
Keywords: Oncology
Breast Cancer
Breast Neoplasms
Drug Therapy-docetaxel
Adjuvants, Pharmaceutic
Excessive Tearing
Issue Date: Jun-2013
Citation: J Clin Oncol. 2013 Jun 10;31(17):2123-7.
Abstract: PURPOSE: To define the incidence and impact of tearing in patients receiving adjuvant docetaxel-based chemotherapy and assess for lacrimal duct obstruction (LDO) as a causative factor. PATIENTS AND METHODS: Consecutive patients with early breast cancer recommended for docetaxel-based chemotherapy with no prior ocular symptoms were included. Before and after completion of chemotherapy, patients underwent lacrimal drainage evaluation by computed tomographic dacrocystography (CT-DCG) and ophthalmic assessment. Eye symptoms were assessed at baseline, during, and after completion of chemotherapy.
DOI: doi: 10.1200/JCO.2012.45.6574.
PubMed URL:
ISSN: 1527-7755
Journal Title: Journal of Clinical Oncology.
Type: Journal Article
Affiliated Organisations: Curtin University and Mount Hospital, Australia.
Medical Oncology, Epworth Hospital, Australia.
Type of Clinical Study or Trial: Observational prospective study.
Appears in Collections:Cancer Services

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