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Title: Cross-validation of a classification system for persons with traumatic brain Injury in the posthospital period.
Epworth Authors: Ponsford, Jennie
Hicks, Amelia
Other Authors: Sander, A. M.
Ngan, E.
Leon-Novelo, L.
Sherer, M.
Keywords: Traumatic Brain Injury
Medical Evidence
Posthospital Period
Cognitive Tests
Neuropsychology Assessment
Monash-Epworth Rehabilitation Research Centre, Epworth Healthcare, Victoria, Australia
Issue Date: Feb-2017
Publisher: Wolters Kluwer
Citation: J Head Trauma Rehabil. 2017 Feb 10.
Abstract: OBJECTIVE: To (1) identify groupings of persons with traumatic brain injury (TBI) in the posthospital period in a cohort recruited in Australia; (2) compare groupings from the Australian cohort to groupings previously developed for a US cohort. SETTING: Rehabilitation centers in the US and Australia. PARTICIPANTS: A total of 170 persons with TBI from Australia and 504 persons with TBI from the United States. Participants were aged 18 to 64 years, greater than 6 months postinjury, had capacity to give consent, and had definitive contemporaneous medical evidence of TBI. DESIGN: Observational study. MAIN MEASURES: Cognitive tests-Wechsler Letter-Number Sequencing and Coding, Rey Auditory Verbal Learning Test, Trail Making Test, Verbal Fluency. Questionnaires-9 scales from the Traumatic Brain Injury Quality-of-Life system; Neurobehavioral Symptom Inventory; Economic Quality of Life, Family Assessment Device-General Functioning. Performance validity-Word Memory Test. RESULTS: Agreement in classification for the 2 samples was only moderate with 63.5% correctly classified and Cohen's κ = 0.53. A post hoc analysis placing all persons showing poor performance validity in the same group improved classification to 73% and Cohen's κ = 0.65 indicating substantial agreement. CONCLUSION: Results provided support for the patient groups developed for the US sample and indicate that these groupings largely replicated in a new cohort.
DOI: 10.1097/HTR.0000000000000290
PubMed URL:
ISSN: 0885-9701
Journal Title: The Journal of Head Trauma Rehabilitation
Type: Journal Article
Affiliated Organisations: TIRR Memorial Hermann, Houston, Texas.
School of Public Health, University of Texas Health Science Center at Houston, Texas.
Yudofsky Division of Neuropsychiatry, Department of Psychiatry, Baylor College of Medicine, Houston, Texas.
Physical Medicine and Rehabilitation, Harris Health System, Houston, Texas.
School of Psychological Sciences, Monash University,Melbourne, Victoria
Type of Clinical Study or Trial: Observational Study
Appears in Collections:Head & Neck

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